| PEG-PCL (Polyethylene glycol-block-polycaprolactone) |
|
| DC-1k10k | PEG-PCL, PEG MW 1000 & PCL MW 10000 |
| DC-1k2k | PEG-PCL, PEG MW 1000 & PCL MW 2000 |
| DC-1k5k | PEG-PCL, PEG MW 1000 & PCL MW 5000 |
| DC-2k10k | PEG-PCL, PEG MW 2000 & PCL MW 10000 |
| DC-2k2k | PEG-PCL, PEG MW 2000 & PCL MW 2000 |
| DC-2k5k | PEG-PCL, PEG MW 2000 & PCL MW 5000 |
| DC-3501k | PEG-PCL, PEG MW 350 & PCL MW 1000 |
| DC-3502k | PEG-PCL, PEG MW 350 & PCL MW 2000 |
| DC-5k10k | PEG-PCL, PEG MW 5000 & PCL MW 10000 |
| DC-5k2k | PEG-PCL, PEG MW 5000 & PCL MW 2000 |
| DC-5k5k | PEG-PCL, PEG MW 5000 & PCL MW 5000 |
Description:
PEG-PCL is an amphiphilic AB diblock copolymer consisting of a hydrophilic block polyethylene glycol (PEG) or polyethylene oxide (PEO) and a hydrophobic block polycaprolactone (PCL). The PEG polymer is capped a methyl ether group, and the hydrophobic block terminates with a hydroxyl group. Biocompatible PEGylated copolymers with biodegradable polyester segments can be used to prepare core-shell micelles, nanoparticles and microspheres. The hydrolytic degradability of the polyester block depends on the molecular weight and the spacer between ester groups (lactide, glycotide or caprolactone).
PEG-PCL with other MWs is also offered.
References:
1) Site-Specific Addressing of Particles and Coatings via Enzyme-Mediated Destabilization, Catalysts 2019, 9, 354, Text.
2) Biodegradable long-circulating polymeric nanospheres. Science 1994;363:1600–3, Text.
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