聚乙二醇-NHS酯 NHS ester PEG| Catalog No. | Product name & molecular weight |
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mPEG-SCM (PEG-NHS: Succinimidyl Carboxyl Methyl ester) 甲氧基-聚乙二醇-琥珀酰亚胺NHS酯 |  | | PJK-208 | mPEG-SCM, MW 350 | | PJK-209 | mPEG-SCM, MW 550 | | PJK-210 | mPEG-SCM, MW 10000 | | PJK-211 | mPEG-SCM, MW 30000 | | PJK-212 | mPEG-SCM, MW 20000 | | PLS-213 | mPEG-SCM, MW 5000 | | PLS-214 | mPEG-SCM, MW 2000 | | PLS-215 | mPEG-SCM, MW 1000 | | PLS-216 | mPEG-SCM, MW 40000 | mPEG-SC (Methoxy PEG Succinimidyl Carbonate NHS Ester) 甲氧基-聚乙二醇-琥珀酰亚胺碳酸酯 |  | | PLS-510 | mPEG-SC, MW 350 | | PLS-511 | mPEG-SC, MW 550 | | PLS-512 | mPEG-SC, MW 1k | | PLS-513 | mPEG-SC, MW 2k | | PLS-514 | mPEG-SC, MW 5k | | PLS-515 | mPEG-SC, MW 10k | | PLS-516 | mPEG-SC, MW 20k | | PLS-517 | mPEG-SC, MW 30k | | PLS-518 | mPEG-SC, MW 40k | mPEG-SG (PEG-NHS: Succinimidyl Glutarate ester) 甲氧基-聚乙二醇-琥珀酰亚胺戊二酸酯 |  | | PSB-216 | mPEG-SG, MW 30,000 | | PSB-2160 | mPEG-SG, MW 40,000 | | PSB-217 | mPEG-SG, MW 20,000 | | PSB-218 | mPEG-SG, MW 550 | | PSB-219 | mPEG-SG, MW 10,000 | | PSB-220 | mPEG-SG, MW 5,000 | | PSB-221 | mPEG-SG, MW 2,000 | | PSB-222 | mPEG-SG, MW 1,000 | mPEG-SS (PEG-NHS: Succinimidyl Succinate ester) 甲氧基-聚乙二醇-琥珀酰亚胺琥珀酸酯 |  | | PSB-2100 | mPEG-SS, MW 550 | | PSB-2101 | mPEG-SS, MW 1,000 | | PSB-2102 | mPEG-SS, MW 2,000 | | PSB-2103 | mPEG-SS, MW 5,000 | | PSB-2104 | mPEG-SS, MW 10,000 | | PSB-2105 | mPEG-SS, MW 20,000 | | PSB-2106 | mPEG-SS, MW 30,000 | | PSB-2107 | mPEG-SS, MW 40,000 | mPEG-GAS (Glutaramide Succinimidyl ester) 甲氧基-聚乙二醇-戊酰胺琥珀酰亚胺酯 |  | | PSB-2080 | mPEG-GAS, MW 550 | | PSB-2081 | mPEG-GAS, MW 1,000 | | PSB-2082 | mPEG-GAS, MW 2,000 | | PSB-2083 | mPEG-GAS, MW 5,000 | | PSB-2084 | mPEG-GAS, MW 10,000 | | PSB-2085 | mPEG-GAS, MW 20,000 | | PSB-2086 | mPEG-GAS, MW 30,000 | | PSB-2087 | mPEG-GAS, MW 40000 | mPEG-SAS (PEG NHS: Succinamide Succinimidyl ester) 甲氧基-聚乙二醇-琥珀酰胺琥珀酰亚胺酯 |  | | PSB-2110 | mPEG-SAS, MW 550 | | PSB-2111 | mPEG-SAS, MW 1,000 | | PSB-2112 | mPEG-SAS, MW 2,000 | | PSB-2113 | mPEG-SAS, MW 5,000 | | PSB-2114 | mPEG-SAS, MW 10,000 | | PSB-2115 | mPEG-SAS, MW 20,000 | | PSB-2116 | mPEG-SAS, MW 30,000 | | PSB-2117 | mPEG-SAS, MW 40,000 | SG-PEG-SG (Bifunctional PEG Succinimidyl Glutarate NHS ester) 琥珀酰亚胺戊二酸酯-聚乙二醇-琥珀酰亚胺戊二酸酯
|  | | PSB-308 | SG-PEG-SG, MW 35k | | PSB-309 | SG-PEG-SG, MW 600 | | PSB-310 | SG-PEG-SG, MW 1k | | PSB-311 | SG-PEG-SG, MW 2k | | PSB-312 | SG-PEG-SG, MW 3.4k | | PSB-313 | SG-PEG-SG, MW 5k | | PSB-314 | SG-PEG-SG, MW 10k | | PSB-315 | SG-PEG-SG, MW 20k | SS-PEG-SS (Bifunctional PEG Succinimidyl Succinate NHS ester) 琥珀酰亚胺琥珀酸酯-聚乙二醇-琥珀酰亚胺琥珀酸酯 |  | | PSB-3300 | SS-PEG-SS, MW 600 | | PSB-3301 | SS-PEG-SS, MW 1k | | PSB-3302 | SS-PEG-SS, MW 2k | | PSB-3303 | SS-PEG-SS, MW 3.4k | | PSB-3304 | SS-PEG-SS, MW 5k | | PSB-3305 | SS-PEG-SS, MW 10k | | PSB-3306 | SS-PEG-SS, MW 20k | GAS-PEG-GAS (Bifunctional PEG Succinimidyl ester NHS-PEG-NHS) 戊酰胺琥珀酰亚胺酯-聚乙二醇-戊酰胺琥珀酰亚胺酯 |  | | PSB-3310 | GAS-PEG-GAS, MW 600 | | PSB-3311 | GAS-PEG-GAS, MW 1k | | PSB-3312 | GAS-PEG-GAS, MW 2k | | PSB-3313 | GAS-PEG-GAS, MW 3.4k | | PSB-3314 | GAS-PEG-GAS, MW 5k | | PSB-3315 | GAS-PEG-GAS, MW 10k | | PSB-3316 | GAS-PEG-GAS, MW 20k | SAS-PEG-SAS (Bifunctional PEG Succinimidyl ester NHS-PEG-NHS) 琥珀酰胺琥珀酰亚胺酯-聚乙二醇-琥珀酰胺琥珀酰亚胺酯 |  | | PSB-3320 | SAS-PEG-SAS, MW 600 | | PSB-3321 | SAS-PEG-SAS, MW 1k | | PSB-3322 | SAS-PEG-SAS, MW 2k | | PSB-3323 | SAS-PEG-SAS, MW 3.4k | | PSB-3324 | SAS-PEG-SAS, MW 5k | | PSB-3325 | SAS-PEG-SAS, MW 10k | | PSB-3326 | SAS-PEG-SAS, MW 20k | SC-PEG-SC (Succinimidyl Carbonate PEG NHS Ester) 琥珀酰亚胺碳酸酯-聚乙二醇-琥珀酰亚胺碳酸酯 |  | | PSB-9010 | SC-PEG-SC, MW 600 | | PSB-9011 | SC-PEG-SC, MW 1k | | PSB-9012 | SC-PEG-SC, MW 2k | | PSB-9013 | SC-PEG-SC, MW 3.4k | | PSB-9014 | SC-PEG-SC, MW 5k | | PSB-9015 | SC-PEG-SC, MW 10k | | PSB-9016 | SC-PEG-SC, MW 20k | | PSB-9017 | SC-PEG-SC, MW 40k | HO-PEG-NHS (Hydroxyl PEG Succinimidyl NHS ester) 羟基-聚乙二醇-琥珀酰亚胺NHS酯 |  | | PHB-1910 | HO-PEG-NHS, MW 1k | | PHB-1911 | HO-PEG-NHS, MW 2k | | PHB-1912 | HO-PEG-NHS, MW 3.4k | | PHB-1913 | HO-PEG-NHS, MW 5k | | PHB-1914 | HO-PEG-NHS, MW 10k | Boc-NH-PEG-SCM (Boc protected amine PEG succinimidyl NHS ester) Boc保护胺-聚乙二醇-琥珀酰亚胺NHS酯 |  | | PHB-966 | Boc-NH-PEG-SCM, MW 1k | | PHB-967 | Boc-NH-PEG-SCM, MW 10k | | PHB-968 | Boc-NH-PEG-SCM, MW 5k | | PHB-969 | Boc-NH-PEG-SCM, MW 2k | | PHB-970 | Boc-NH-PEG-SCM, MW 3.4k | Fmoc-NH-PEG-SCM (Fmoc protected Amine PEG Succinimidyl NHS ester) Fmoc保护胺-聚乙二醇-琥珀酰亚胺NHS酯 |  | | PHB-972 | Fmoc-NH-PEG-SCM, MW 1k | | PHB-973 | Fmoc-NH-PEG-SCM, MW 3.4k | | PHB-974 | Fmoc-NH-PEG-SCM, MW 5k | | PHB-975 | Fmoc-NH-PEG-SCM, MW 2k | | PHB-976 | Fmoc-NH-PEG-SCM, MW 10k | MAL-PEG-SCM (Maleimide PEG Succinimidyl NHS acid ester) 马来酰亚胺-聚乙二醇-琥珀酰亚胺NHS酯 |  | | PHB-950 | MAL-PEG-SCM, MW 2k | | PHB-951 | MAL-PEG-SCM, MW 3.4k | | PHB-952 | MAL-PEG-SCM, MW 5k | | PHB-953 | MAL-PEG-SCM, MW 10k | | PHB-954 | MAL-PEG-SCM, MW 1k | OPSS-PEG-NHS (Orthopyridyl disulfide PDP PEG Succinimidyl ester) 吡啶基二硫醚-聚乙二醇-琥珀酰亚胺NHS酯 |  | | PHB-994 | OPSS-PEG-NHS, MW 1k | | PHB-995 | OPSS-PEG-NHS, MW 2k | | PHB-996 | OPSS-PEG-NHS, MW 3.4k | | PHB-997 | OPSS-PEG-NHS, MW 5k | | PHB-998 | OPSS-PEG-NHS, MW 10k | | ACA-PEG-SCM (Acrylamide PEG NHS ester) | | 丙烯酰胺-聚乙二醇-琥珀酰亚胺NHS酯 末端双键 | | PHB-1970 | ACA-PEG-SCM, MW 2k | | PHB-1971 | ACA-PEG-SCM, MW 3.4k | | PHB-1972 | ACA-PEG-SCM, MW 5k | | PHB-1973 | ACA-PEG-SCM, MW 10k | | PHB-1974 | ACA-PEG-SCM, MW 1k | AC-PEG-SCM (Acrylate PEG Succinimidyl NHS ester) 丙烯酸酯-聚乙二醇-琥珀酰亚胺NHS酯 末端双键 |  | | PHB-960 | AC-PEG-SCM, MW 2k | | PHB-961 | AC-PEG-SCM, MW 3.4k | | PHB-962 | AC-PEG-SCM, MW 5k | | PHB-963 | AC-PEG-SCM, MW 10k | | PHB-964 | AC-PEG-SCM, MW 1k | Biotin-PEG-SCM (Biotin PEG Succinimidyl NHS ester) 生物素-聚乙二醇-琥珀酰亚胺NHS酯 |  | | PJK-1900 | Biotin-PEG-SCM, MW 2k | | PJK-1901 | Biotin-PEG-SCM, MW 3.4k | | PJK-1902 | Biotin-PEG-SCM, MW 5k | | PJK-1903 | Biotin-PEG-SCM, MW 10k | | PJK-1904 | Biotin-PEG-SCM, MW 1k | 4-Arm PEG-SCM (Multi-arm - four arm - PEG Succinimidyl NHS ester) 4臂星形-聚乙二醇-琥珀酰亚胺NHS酯 |  | | PSB-485 | 4-Arm PEG-SCM, MW 2k | | PSB-486 | 4-Arm PEG-SCM, MW 10k | | PSB-487 | 4-Arm PEG-SCM, MW 20k | | PSB-488 | 4-Arm PEG-SCM, MW 5k | 4-Arm PEG-SC (Multi Armed PEG Succinimidyl Carbonate NHS Ester) 4臂星形-聚乙二醇-琥珀酰亚胺碳酸酯 | | | PSB-4411 | 4-Arm PEG-SC, MW 2k | | PSB-4412 | 4-Arm PEG-SC, MW 5k | | PSB-4413 | 4-Arm PEG-SC, MW 10k | | PSB-4414 | 4-Arm PEG-SC, MW 20k | 4-Arm PEG-SG (Multi-arm - four arm - PEG Succinimidyl Glutarate) 4臂星形-聚乙二醇-琥珀酰亚胺戊二酸酯 | | | PSB-460 | 4-Arm PEG-SG, MW 2k | | PSB-461 | 4-Arm PEG-SG, MW 10k | | PSB-463 | 4-Arm PEG-SG, MW 5k | | PSB-465 | 4-Arm PEG-SG, MW 20k | 4-Arm PEG-SS (Multi-arm - four arm - PEG Succinimidyl Succinate) 4臂星形-聚乙二醇-琥珀酰亚胺琥珀酸酯 | | | PSB-4010 | 4-Arm PEG-SS, MW 2k | | PSB-4011 | 4-Arm PEG-SS, MW 5k | | PSB-4012 | 4-Arm PEG-SS, MW 10k | | PSB-4015 | 4-Arm PEG-SS, MW 20k | 4-Arm PEG-GAS (Multi-arm - four arm - PEG Succinimidyl NHS ester) 4臂星形-聚乙二醇-戊酰胺琥珀酰亚胺酯 | | | PSB-4020 | 4-Arm PEG-GAS, MW 2k | | PSB-4021 | 4-Arm PEG-GAS, MW 5k | | PSB-4022 | 4-Arm PEG-GAS, MW 10k | | PSB-4025 | 4-Arm PEG-GAS, MW 20k | 4-Arm PEG-SAS (Multi-arm - four arm - PEG Succinimidyl NHS ester) 4臂星形-聚乙二醇-琥珀酰胺琥珀酰亚胺酯 | | | PSB-4030 | 4-Arm PEG-SAS, MW 2k | | PSB-4031 | 4-Arm PEG-SAS, MW 5k | | PSB-4032 | 4-Arm PEG-SAS, MW 10k | | PSB-4035 | 4-Arm PEG-SAS, MW 20k | 8-Arm PEG-SCM (Multi-arm - eight arm - PEG Succinimidyl NHS ester) 8臂星形-聚乙二醇-琥珀酰亚胺NHS酯 | | | PSB-841 | 8-Arm PEG-SCM, MW 10k | | PSB-842 | 8-Arm PEG-SCM, MW 20k | | PSB-844 | 8-Arm PEG-SCM, MW 40k | 8-Arm PEG-SG (Multi-arm - eight arm - PEG Succinimidyl NHS ester) 8臂星形-聚乙二醇-琥珀酰亚胺戊二酸酯 | | | PSB-846 | 8-Arm PEG-SG, MW 10k | | PSB-847 | 8-Arm PEG-SG, MW 20k | | PSB-849 | 8-Arm PEG-SG, MW 40k | 8-Arm PEG-SS (Multi-arm - eight arm - PEG Succinimidyl NHS ester) 8臂星形-聚乙二醇-琥珀酰亚胺琥珀酸酯 | | | PSB-8041 | 8-Arm PEG-SS, MW 10k | | PSB-8042 | 8-Arm PEG-SS, MW 20k | | PSB-8044 | 8-Arm PEG-SS, MW 40k | 8-Arm PEG-GAS (Multi-arm - eight arm - PEG Succinimidyl NHS ester) 8臂星形-聚乙二醇-戊酰胺琥珀酰亚胺酯 | | | PSB-8051 | 8-Arm PEG-GAS, MW 10k | | PSB-8052 | 8-Arm PEG-GAS, MW 20k | | PSB-8054 | 8-Arm PEG-GAS, MW 40k | 8-Arm PEG-SAS (Multi-arm - eight arm - PEG Succinimidyl NHS ester) 8臂星形-聚乙二醇-琥珀酰胺琥珀酰亚胺酯 | | | PSB-8061 | 8-Arm PEG-SAS, MW 10k | | PSB-8062 | 8-Arm PEG-SAS, MW 20k | | PSB-8064 | 8-Arm PEG-SAS, MW 40k | C18-PEG4-NHS (Tetraethylene glycol octadecyl succinimidyl ester) 十八烷基醚-低聚四乙二醇-NHS酯 | | | PMD-7005 | C18-PEG4-NHS, PEG MW 176 Da | C18-PEG6-NHS (Hexaethylene glycol octadecyl succinimidyl ester) 十八烷基醚-低聚六乙二醇-NHS酯 | | | PMD-7025 | C18-PEG6-NHS, PEG MW 264 Da | C18-PEG12-NHS (Dodecaethylene glycol octadecyl succinimidyl ester) 十八烷基醚-低聚十二乙二醇-NHS酯 | | | PMD-7045 | C18-PEG12-NHS, PEG MW 528 Da | | Pyrene-PEG-NHS Ester | | 芘-聚乙二醇-NHS酯 | | PBL-9031 | Pyrene-PEG-NHS Ester, MW 1k | | PBL-9032 | Pyrene-PEG-NHS Ester, MW 2k | | PBL-9033 | Pyrene-PEG-NHS Ester, MW 3.4k | | PBL-9034 | Pyrene-PEG-NHS Ester, MW 5k | | PBL-9035 | Pyrene-PEG-NHS Ester, MW 10k | Acetal-PEG-NHS (Protected Aldehyde PEG NHS Ester) 缩醛-聚乙二醇-NHS酯 | | | PJK-1701 | Acetal-PEG-NHS, MW 1k | | PJK-1702 | Acetal-PEG-NHS, MW 2k | | PJK-1703 | Acetal-PEG-NHS, MW 3.4k | | PJK-1704 | Acetal-PEG-NHS, MW 5k | | PJK-1705 | Acetal-PEG-NHS, MW 10k |
Q: What are the differences among your PEG NHS ester & PEG Acid products? A: We offer a variety of PEG Acid and PEG NHS ester. These NHS esters react with primary and secondary amine to form a stable amide linkage. This reaction may be carried out in an organic solution with an organic base or may be carried out in an aqueous solution at or around neutral pH or slightly acidic or basic. To PEGylate proteins or nanoparticles, it often requires a large excess of PEG NHS esters due to the competitive hydrolysis reaction in an aqueous solution. Stability of NHS esters is compared by their hydrolysis half-life (T1/2). To mitigate the competitive hydrolysis reaction, organic solvents such as amine-free, anhydrous DMF and DMSO may be used in combination with an aqueous buffer solution. PEG NHS esters | Structural characteristics | Amine reactivity | Stability |
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| Type A: SCM | Methylene (CH2) linkage between PEG and NHS ester | Highly reactive | Hydrolysis half-life: less than five minutes. It often requires the use of a large excess of PEG reagents. | | Type B: SG | C4 aliphatic ester linkage between PEG and NHS ester | Very reactive | Hydrolysis half-life: around 20 minutes. | | Type C: SS | C3 aliphatic ester linkage between PEG and NHS ester | Very reactive | Hydrolysis half-life: around 10 minutes. | | Type D: GAS | C4 aliphatic amide linkage between PEG and NHS ester | Very reactive | Hydrolysis half-life: around 20 minutes. | | Type E: SAS | C3 aliphatic amide linkage between PEG and NHS ester | Very reactive | Hydrolysis half-life: around 10 minutes. |
SCM: Succinimidyl Carboxyl Methyl ester; SG: Succinimidyl Glutarate ester; SS: Succinimidyl Succinate ester; GAS: GlutarAmide Succinimidyl ester; SAS: SuccinAmide Succinimidyl ester. Note: hydrolysis half-life depends on pH, temperature and other factors of the testing conditions. | PEG acids | Structural characteristics |
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| Type A: AA | Methylene (CH2) linkage between PEG and acid (COOH) | | Type B: GA | C4 aliphatic ester linkage between PEG and acid (COOH) | | Type C: SA | C3 aliphatic ester linkage between PEG and acid (COOH) | | Type D: GAA | C4 aliphatic amide linkage between PEG and acid (COOH) | | Type E: SAA | C3 aliphatic amide linkage between PEG and acid (COOH) |
AA: Acetic Acid, also called CM - Carboxyl Methyl; GA: Glutaric Acid; SA: Succinic Acid; GAA: GlutarAmide Acid; SAS: SuccinAmide Acid.
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