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同双官能团聚乙二醇 Creative PEGWorks 高分子试剂 Homobifunctional PEG
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同双官能团聚乙二醇 Creative PEGWorks 高分子试剂 Homobifunctional PEG
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同双官能团聚乙二醇

Homobifunctional PEG

Catalog No.Product name & molecular weight

MAL-PEG-MAL (Bifunctional Maleimide PEG Maleimide)

马来酰亚胺-聚乙二醇-马来酰亚胺

PSB-300MAL-PEG-MAL, MW 2k
PSB-301MAL-PEG-MAL, MW 3.4k
PSB-302MAL-PEG-MAL, MW 5k
PSB-303MAL-PEG-MAL, MW 1k
PSB-304MAL-PEG-MAL, MW 10k
PSB-305MAL-PEG-MAL, MW 20k
PSB-306MAL-PEG-MAL, MW 600
HO-PEG-OH (Polyethylene glycol)
羟基-聚乙二醇-羟基
PSB-035HO-PEG-OH, MW 35k

OPSS-PEG-OPSS (OPSS: orthopyridyl disulfide; PDP-PEG-PDP)

吡啶基二硫醚-聚乙二醇-吡啶基二硫醚

PSB-380OPSS-PEG-OPSS, MW 2k
PSB-381OPSS-PEG-OPSS, MW 3.4k
PSB-382OPSS-PEG-OPSS, MW 5k
PSB-383OPSS-PEG-OPSS, MW 1k
PSB-384OPSS-PEG-OPSS, MW 10k
PSB-385OPSS-PEG-OPSS, MW 20k
PSB-386OPSS-PEG-OPSS, MW 600

HS-PEG-SH (Bifunctional Thiol PEG Thiol)

硫醇-聚乙二醇-硫醇

PLS-608HS-PEG-SH, MW 20k
PLS-612HS-PEG-SH, MW 3.4k
PLS-614HS-PEG-SH, MW 5k
PSB-609HS-PEG-SH, MW 10k
PSB-610HS-PEG-SH, MW 600
PSB-611HS-PEG-SH, MW 1k
PSB-613HS-PEG-SH, MW 2k
PSB-615HS-PEG-SH, MW 35k

VS-PEG-VS (Vinylsulfone-PEG-Vinylsulfone)

乙烯基砜-聚乙二醇-乙烯基砜

PSB-3221VS-PEG-VS, MW 1k
PSB-3222VS-PEG-VS, MW 2k
PSB-3223VS-PEG-VS, MW 3.4k
PSB-3224VS-PEG-VS, MW 5k
PSB-3225VS-PEG-VS, MW 10k
PSB-3226VS-PEG-VS, MW 20k

SG-PEG-SG (Bifunctional PEG Succinimidyl Glutarate NHS ester)

琥珀酰亚胺戊二酸酯-聚乙二醇-琥珀酰亚胺戊二酸酯

PSB-308SG-PEG-SG, MW 35k
PSB-309SG-PEG-SG, MW 600
PSB-310SG-PEG-SG, MW 1k
PSB-311SG-PEG-SG, MW 2k
PSB-312SG-PEG-SG, MW 3.4k
PSB-313SG-PEG-SG, MW 5k
PSB-314SG-PEG-SG, MW 10k
PSB-315SG-PEG-SG, MW 20k

SS-PEG-SS (Bifunctional PEG Succinimidyl Succinate NHS ester)

琥珀酰亚胺琥珀酸酯-聚乙二醇-琥珀酰亚胺琥珀酸酯

PSB-3300SS-PEG-SS, MW 600
PSB-3301SS-PEG-SS, MW 1k
PSB-3302SS-PEG-SS, MW 2k
PSB-3303SS-PEG-SS, MW 3.4k
PSB-3304SS-PEG-SS, MW 5k
PSB-3305SS-PEG-SS, MW 10k
PSB-3306SS-PEG-SS, MW 20k

GAS-PEG-GAS (Bifunctional PEG Succinimidyl ester NHS-PEG-NHS)

戊酰胺琥珀酰亚胺酯-聚乙二醇-戊酰胺琥珀酰亚胺酯

PSB-3310GAS-PEG-GAS, MW 600
PSB-3311GAS-PEG-GAS, MW 1k
PSB-3312GAS-PEG-GAS, MW 2k
PSB-3313GAS-PEG-GAS, MW 3.4k
PSB-3314GAS-PEG-GAS, MW 5k
PSB-3315GAS-PEG-GAS, MW 10k
PSB-3316GAS-PEG-GAS, MW 20k

SAS-PEG-SAS (Bifunctional PEG Succinimidyl ester NHS-PEG-NHS)

琥珀酰胺琥珀酰亚胺酯-聚乙二醇-琥珀酰胺琥珀酰亚胺酯

PSB-3320SAS-PEG-SAS, MW 600
PSB-3321SAS-PEG-SAS, MW 1k
PSB-3322SAS-PEG-SAS, MW 2k
PSB-3323SAS-PEG-SAS, MW 3.4k
PSB-3324SAS-PEG-SAS, MW 5k
PSB-3325SAS-PEG-SAS, MW 10k
PSB-3326SAS-PEG-SAS, MW 20k

Amine-PEG-Amine (Bifunctional PEG Amine NH2-PEG-NH2)

胺-聚乙二醇-胺

PSB-330Amine-PEG-Amine, MW 2k
PSB-331Amine-PEG-Amine, MW 3.4k
PSB-332Amine-PEG-Amine, MW 5k
PSB-334Amine-PEG-Amine, MW 10k
PSB-335Amine-PEG-Amine, MW 20k
PSB-336Amine-PEG-Amine, MW 1k
PSB-3360Amine-PEG-Amine, MW 600
PSB-3635Amine-PEG-Amine, MW 35k
PSB-3640Amine-PEG-Amine, MW 400

AC-PEG-AC (Polyethylene Glycol Diacrylate PEGDA Acrylate Crosslinker)

丙烯酸酯-聚乙二醇-丙烯酸酯 末端双键

PSB-341AC-PEG-AC, MW 35k
PSB-342AC-PEG-AC, MW 600
PSB-343AC-PEG-AC, MW 1k
PSB-345AC-PEG-AC, MW 5k
PSB-346AC-PEG-AC, MW 2k
PSB-347AC-PEG-AC, MW 3.4k
PSB-348AC-PEG-AC, MW 10k
PSB-349AC-PEG-AC, MW 20k

Methacrylate-PEG-Methacrylate

甲基丙烯酸酯-聚乙二醇-甲基丙烯酸酯 末端双键

PSB-3470Methacrylate-PEG-Methacrylate, MW 4k
PSB-3471Methacrylate-PEG-Methacrylate, MW 600
PSB-3472Methacrylate-PEG-Methacrylate, MW 1k
PSB-3473Methacrylate-PEG-Methacrylate, MW 2k
PSB-3474Methacrylate-PEG-Methacrylate, MW 3.4k
PSB-3475Methacrylate-PEG-Methacrylate, MW 5k
PSB-3476Methacrylate-PEG-Methacrylate, MW 8k
PSB-3477Methacrylate-PEG-Methacrylate, MW 10k
PSB-3478Methacrylate-PEG-Methacrylate, MW 20k
PSB-3479Methacrylate-PEG-Methacrylate, MW 3k

ACA-PEG-ACA (Polymerizable PEG Di-Acrylamide (ACA: Acrylamide))

丙烯酰胺-聚乙二醇-丙烯酰胺 末端双键

PSB-3330ACA-PEG-ACA, MW 600
PSB-3331ACA-PEG-ACA, MW 1k
PSB-3332ACA-PEG-ACA, MW 2k
PSB-3333ACA-PEG-ACA, MW 3.4k
PSB-3334ACA-PEG-ACA, MW 5k
PSB-3335ACA-PEG-ACA, MW 10k
PSB-3336ACA-PEG-ACA, MW 20k
PSB-3337ACA-PEG-ACA, MW 35k

Epoxide-PEG-Epoxide (EP-PEG-EP, PEG Di-Glycidyl Ether)

环氧基-聚乙二醇-环氧基

PSB-350Epoxide-PEG-Epoxide, MW 2k
PSB-351Epoxide-PEG-Epoxide, MW 3.4k
PSB-352Epoxide-PEG-Epoxide, MW 5k
PSB-353Epoxide-PEG-Epoxide, MW 1k
PSB-354Epoxide-PEG-Epoxide, MW 10k
PSB-355Epoxide-PEG-Epoxide, MW 20k
PSB-356Epoxide-PEG-Epoxide, MW 600

NPC-PEG-NPC (Bifunctional NPC PEG, Nitrophenyl Carbonate)

硝基苯碳酸酯-聚乙二醇-硝基苯碳酸酯

PLS-391NPC-PEG-NPC, MW 3.4k
PSB-390NPC-PEG-NPC, MW 2k
PSB-392NPC-PEG-NPC, MW 5k
PSB-393NPC-PEG-NPC, MW 1k
PSB-394NPC-PEG-NPC, MW 10k
PSB-395NPC-PEG-NPC, MW 20k
PSB-396NPC-PEG-NPC, MW 600

Aldehyde-PEG-Aldehyde (ALD-PEG-ALD, bifunctional PEG propionaldehyde)

醛基-聚乙二醇-醛基

PSB-316Aldehyde-PEG-Aldehyde, MW 600
PSB-317Aldehyde-PEG-Aldehyde, MW 1k
PSB-318Aldehyde-PEG-Aldehyde, MW 2k
PSB-319Aldehyde-PEG-Aldehyde, MW 3.4k
PSB-321Aldehyde-PEG-Aldehyde, MW 5k
PSB-322Aldehyde-PEG-Aldehyde, MW 10k
PSB-323Aldehyde-PEG-Aldehyde, MW 20k

AA-PEG-AA (Acid-PEG-Acid, AA - acetic acid or carboxyl methyl)

乙酸-聚乙二醇-乙酸

PSB-360AA-PEG-AA, MW 600
PSB-361AA-PEG-AA, MW 1k
PSB-362AA-PEG-AA, MW 2k
PSB-363AA-PEG-AA, MW 3.4k
PSB-364AA-PEG-AA, MW 5k
PSB-365AA-PEG-AA, MW 10k
PSB-366AA-PEG-AA, MW 20k

GA-PEG-GA (Acid - PEG - Acid, GA: Glutaric acid)

戊二酸-聚乙二醇-戊二酸

PSB-367GA-PEG-GA, MW 600
PSB-368GA-PEG-GA, MW 1k
PSB-369GA-PEG-GA, MW 2k
PSB-370GA-PEG-GA, MW 3.4k
PSB-371GA-PEG-GA, MW 5k
PSB-372GA-PEG-GA, MW 10k
PSB-373GA-PEG-GA, MW 20k
PSB-374GA-PEG-GA, MW 35k

SA-PEG-SA (Bifunctional PEG carboxylic acid - Succinic Acid)

琥珀酸-聚乙二醇-琥珀酸

PSB-3340SA-PEG-SA, MW 600
PSB-3341SA-PEG-SA, MW 1k
PSB-3342SA-PEG-SA, MW 2k
PSB-3343SA-PEG-SA, MW 3.4k
PSB-3344SA-PEG-SA, MW 5k
PSB-3345SA-PEG-SA, MW 10k
PSB-3346SA-PEG-SA, MW 20k

GAA-PEG-GAA (Bifunctional PEG carboxylic acid, Glutaramide Acid)

戊二酰胺酸-聚乙二醇-戊二酰胺酸

PSB-3350GAA-PEG-GAA, MW 600
PSB-3351GAA-PEG-GAA, MW 1k
PSB-3352GAA-PEG-GAA, MW 2k
PSB-3353GAA-PEG-GAA, MW 3.4k
PSB-3354GAA-PEG-GAA, MW 5k
PSB-3355GAA-PEG-GAA, MW 10k
PSB-3356GAA-PEG-GAA, MW 20k

SAA-PEG-SAA (Bifunctional PEG carboxylic acid, Succinamide Acid)

琥珀酰胺酸-聚乙二醇-琥珀酰胺酸

PSB-3370SAA-PEG-SAA, MW 600
PSB-3371SAA-PEG-SAA, MW 1k
PSB-3372SAA-PEG-SAA, MW 2k
PSB-3373SAA-PEG-SAA, MW 3.4k
PSB-3374SAA-PEG-SAA, MW 5k
PSB-3375SAA-PEG-SAA, MW 10k
PSB-3376SAA-PEG-SAA, MW 20k

SC-PEG-SC (Succinimidyl Carbonate PEG NHS Ester)

琥珀酰亚胺碳酸酯-聚乙二醇-琥珀酰亚胺碳酸酯

PSB-9010SC-PEG-SC, MW 600
PSB-9011SC-PEG-SC, MW 1k
PSB-9012SC-PEG-SC, MW 2k
PSB-9013SC-PEG-SC, MW 3.4k
PSB-9014SC-PEG-SC, MW 5k
PSB-9015SC-PEG-SC, MW 10k
PSB-9016SC-PEG-SC, MW 20k
PSB-9017SC-PEG-SC, MW 40k

Azide-PEG-Azide (Bifunctional PEG azide, N3-PEG-N3)

叠氮基-聚乙二醇-叠氮基

PSB-324Azide-PEG-Azide, MW 1k
PSB-3241Azide-PEG-Azide, MW 600
PSB-325Azide-PEG-Azide, MW 2k
PSB-326Azide-PEG-Azide, MW 3.4k
PSB-327Azide-PEG-Azide, MW 5k
PSB-328Azide-PEG-Azide, MW 10k
PSB-329Azide-PEG-Azide, MW 20k

Alkyne-PEG-Alkyne (Bifunctional alkyne or acetylene PEG)

炔基-聚乙二醇-炔基 末端三键

PSB-3361Alkyne-PEG-Alkyne, MW 1k
PSB-3362Alkyne-PEG-Alkyne, MW 600
PSB-337Alkyne-PEG-Alkyne, MW 2k
PSB-338Alkyne-PEG-Alkyne, MW 3.4k
PSB-339Alkyne-PEG-Alkyne, MW 5k
PSB-3390Alkyne-PEG-Alkyne, MW 10k
PSB-3391Alkyne-PEG-Alkyne, MW 20k

Biotin-PEG-Biotin (Bifunctional biotin PEG linker)

生物素-聚乙二醇-生物素

PSB-3363Biotin-PEG-Biotin, MW 600
PSB-3364Biotin-PEG-Biotin, MW 1k
PSB-3365Biotin-PEG-Biotin, MW 2k
PSB-3366Biotin-PEG-Biotin, MW 3.4k
PSB-3367Biotin-PEG-Biotin, MW 5k
PSB-3368Biotin-PEG-Biotin, MW 10k
PSB-3369Biotin-PEG-Biotin, MW 20k
PSB-3435Biotin-PEG-Biotin, MW 35000

Silane-PEG-Silane (Bifunctional silane PEG)

硅烷-聚乙二醇-硅烷

PSB-3380Silane-PEG-Silane, MW 600
PSB-3381Silane-PEG-Silane, MW 1k
PSB-3382Silane-PEG-Silane, MW 2k
PSB-3383Silane-PEG-Silane, MW 3.4k
PSB-3384Silane-PEG-Silane, MW 5k
PSB-3385Silane-PEG-Silane, MW 10k
PSB-3386Silane-PEG-Silane, MW 20k

Hydrazide-PEG-Hydrazide (Bifunctional PEG Hydrazide)

酰肼-聚乙二醇-酰肼

PSB-3401Hydrazide-PEG-Hydrazide, MW 600
PSB-3402Hydrazide-PEG-Hydrazide, MW 1k
PSB-3403Hydrazide-PEG-Hydrazide, MW 2k
PSB-3404Hydrazide-PEG-Hydrazide, MW 3.4k
PSB-3405Hydrazide-PEG-Hydrazide, MW 5k
PSB-3406Hydrazide-PEG-Hydrazide, MW 10k
PSB-3407Hydrazide-PEG-Hydrazide, MW 20k

Tosylate-PEG-Tosylate (Bifunctional PEG Tosyl)

甲苯磺酸酯-聚乙二醇-甲苯磺酸酯

PSB-3411Tosylate-PEG-Tosylate, MW 600
PSB-3412Tosylate-PEG-Tosylate, MW 1k
PSB-3413Tosylate-PEG-Tosylate, MW 2k
PSB-3414Tosylate-PEG-Tosylate, MW 3.4k
PSB-3415Tosylate-PEG-Tosylate, MW 5k
PSB-3416Tosylate-PEG-Tosylate, MW 10k
PSB-3417Tosylate-PEG-Tosylate, MW 20k

Chloride-PEG-Chloride (Bifunctional PEG Halide)

氯-聚乙二醇-氯

PSB-3421Chloride-PEG-Chloride, MW 600
PSB-3422Chloride-PEG-Chloride, MW 1k
PSB-3423Chloride-PEG-Chloride, MW 2k
PSB-3424Chloride-PEG-Chloride, MW 3.4k
PSB-3425Chloride-PEG-Chloride, MW 5k
PSB-3426Chloride-PEG-Chloride, MW 10k
PSB-3427Chloride-PEG-Chloride, MW 20k

Norbornene-PEG-Norbornene

降冰片烯-聚乙二醇-降冰片烯

PSB-200Norbornene-PEG-Norbornene, MW 2k
PSB-201Norbornene-PEG-Norbornene, MW 3.4k
PSB-202Norbornene-PEG-Norbornene, MW 6k
PSB-203Norbornene-PEG-Norbornene, MW 10k
PSB-204Norbornene-PEG-Norbornene, MW 20k

DBCO-PEG-DBCO (DBCO Azide Click PEG)

二苯并环辛烯-聚乙二醇-二苯并环辛烯(DBCO点击化学试剂)

PSB-7010DBCO-PEG-DBCO, MW 1k
PSB-7011DBCO-PEG-DBCO, MW 2k
PSB-7012DBCO-PEG-DBCO, MW 5k
PSB-7013DBCO-PEG-DBCO, MW 10k
PSB-7014DBCO-PEG-DBCO, MW 20k

Alkene-PEG-Alkene

烯烃-聚乙二醇-烯烃 


PSB-3651Alkene-PEG-Alkene, MW 1k

Carbonylacrylic-PEG-Carbonylacrylic (Maleimide-PEG Alternative)

羰基丙烯酰胺-聚乙二醇-羰基丙烯酰胺(马来酰亚胺-PEG替代品)

PSB-6111Carbonylacrylic-PEG-Carbonylacrylic, MW 1k
PSB-6112Carbonylacrylic-PEG-Carbonylacrylic, MW 2k
PSB-6113Carbonylacrylic-PEG-Carbonylacrylic, MW 3.4k
PSB-6114Carbonylacrylic-PEG-Carbonylacrylic, MW 5k
PSB-6115Carbonylacrylic-PEG-Carbonylacrylic, MW 10k
PSB-6116Carbonylacrylic-PEG-Carbonylacrylic, MW 20k



Q: What are the differences among your PEG NHS ester & PEG Acid products?
A: We offer a variety of PEG Acid and PEG NHS ester. These NHS esters react with primary and secondary amine to form a stable amide linkage. This reaction may be carried out in an organic solution with an organic base or may be carried out in an aqueous solution at or around neutral pH or slightly acidic or basic. To PEGylate proteins or nanoparticles, it often requires a large excess of PEG NHS esters due to the competitive hydrolysis reaction in an aqueous solution. Stability of NHS esters is compared by their hydrolysis half-life (T1/2). To mitigate the competitive hydrolysis reaction, organic solvents such as amine-free, anhydrous DMF and DMSO may be used in combination with an aqueous buffer solution.

PEG NHS

esters

Structural characteristics

Amine

reactivity

Stability
Type A: SCMMethylene (CH2) linkage between PEG and NHS esterHighly reactiveHydrolysis half-life: less than five minutes. It often requires the use of a large excess of PEG reagents.
Type B: SGC4 aliphatic ester linkage between PEG and NHS esterVery reactiveHydrolysis half-life: around 20 minutes.
Type C: SSC3 aliphatic ester linkage between PEG and NHS esterVery reactiveHydrolysis half-life: around 10 minutes.
Type D: GASC4 aliphatic amide linkage between PEG and NHS esterVery reactiveHydrolysis half-life: around 20 minutes.
Type E: SASC3 aliphatic amide linkage between PEG and NHS esterVery reactiveHydrolysis half-life: around 10 minutes.

SCM: Succinimidyl Carboxyl Methyl ester; SG: Succinimidyl Glutarate ester; SS: Succinimidyl Succinate ester; GAS: GlutarAmide Succinimidyl ester; SAS: SuccinAmide Succinimidyl ester. Note: hydrolysis half-life depends on pH, temperature and other factors of the testing conditions.

PEG acidsStructural characteristics
Type A: AAMethylene (CH2) linkage between PEG and acid (COOH)
Type B: GAC4 aliphatic ester linkage between PEG and acid (COOH)
Type C: SAC3 aliphatic ester linkage between PEG and acid (COOH)
Type D: GAAC4 aliphatic amide linkage between PEG and acid (COOH)
Type E: SAAC3 aliphatic amide linkage between PEG and acid (COOH)
AA: Acetic Acid, also called CM - Carboxyl Methyl; GA: Glutaric Acid; SA: Succinic Acid; GAA: GlutarAmide Acid; SAS: SuccinAmide Acid.




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