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8臂星形-聚乙二醇系列 Creative PEGWorks 高分子试剂 8-Arm PEG
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8臂星形-聚乙二醇系列 Creative PEGWorks 高分子试剂 8-Arm PEG
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品牌: Creative PEGWorks
产地: 美国
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8臂星形-聚乙二醇系列

8-Arm PEG

Catalog No.Product name & molecular weight

8-Arm PEG-OH (Multi-arm - eight arm - Polyethylene Glycol)

8臂星形-聚乙二醇-羟基

PSB-8018-Arm PEG-OH, MW 10k
PSB-8028-Arm PEG-OH, MW 20k
PSB-8048-Arm PEG-OH, MW 40k

8-Arm PEG-NH2 (Multi-arm - eight arm - PEG Amine)

8臂星形-聚乙二醇-胺

PSB-8118-Arm PEG-NH2, MW 10k
PSB-8128-Arm PEG-NH2, MW 20k
PSB-8148-Arm PEG-NH2, MW 40k

8-Arm PEG-Acrylate (Multi-arm - eight arm - PEG Acrylate)

8臂星形-聚乙二醇-丙烯酸酯(末端双键)

PSB-8218-Arm PEG-Acrylate, MW 10k
PSB-8228-Arm PEG-Acrylate, MW 20k
PSB-8248-Arm PEG-Acrylate, MW 40k

8-Arm PEG-Acrylamide (Multi-arm - eight arm - PEG Acrylamide)

8臂星形-聚乙二醇-丙烯酰胺(末端双键)

PSB-8268-Arm PEG-Acrylamide, MW 10k
PSB-8278-Arm PEG-Acrylamide, MW 20k
PSB-8288-Arm PEG-Acrylamide, MW 40k

8-Arm PEG-Acid (Multi-arm - eight arm - PEG Carboxylic Acid COOH)

8臂星形-聚乙二醇-羧酸

PSB-8318-Arm PEG-Acid, MW 10k
PSB-8328-Arm PEG-Acid, MW 20k
PSB-8348-Arm PEG-Acid, MW 40k

8-Arm PEG-GA (Multi-arm - eight arm - PEG Glutaric Acid)

8臂星形-聚乙二醇-戊二酸

PSB-8368-Arm PEG-GA, MW 10k
PSB-8378-Arm PEG-GA, MW 20k
PSB-8398-Arm PEG-GA, MW 40k

8-Arm PEG-SA (Multi-arm - eight arm - PEG Succinic Acid)

8臂星形-聚乙二醇-琥珀酸

PSB-80118-Arm PEG-SA, MW 10k
PSB-80128-Arm PEG-SA, MW 20k
PSB-80148-Arm PEG-SA, MW 40k

8-Arm PEG-GAA (Multi-arm - eight arm - PEG Carboxylic Acid COOH)

8臂星形-聚乙二醇-戊二酰胺酸

PSB-80218-Arm PEG-GAA, MW 10k
PSB-80228-Arm PEG-GAA, MW 20k
PSB-80238-Arm PEG-GAA, MW 40k

8-Arm PEG-SAA (Multi-arm - eight arm - PEG Carboxylic Acid COOH)

8臂星形-聚乙二醇-琥珀酰胺酸

PSB-80318-Arm PEG-SAA, MW 10k
PSB-80328-Arm PEG-SAA, MW 20k
PSB-80348-Arm PEG-SAA, MW 40k

8-Arm PEG-SCM (Multi-arm - eight arm - PEG Succinimidyl NHS ester)

8臂星形-聚乙二醇-琥珀酰亚胺NHS酯

PSB-8418-Arm PEG-SCM, MW 10k
PSB-8428-Arm PEG-SCM, MW 20k
PSB-8448-Arm PEG-SCM, MW 40k

8-Arm PEG-SG (Multi-arm - eight arm - PEG Succinimidyl NHS ester)

8臂星形-聚乙二醇-琥珀酰亚胺戊二酸酯

PSB-8468-Arm PEG-SG, MW 10k
PSB-8478-Arm PEG-SG, MW 20k
PSB-8498-Arm PEG-SG, MW 40k

8-Arm PEG-SS (Multi-arm - eight arm - PEG Succinimidyl NHS ester)

8臂星形-聚乙二醇-琥珀酰亚胺琥珀酸酯

PSB-80418-Arm PEG-SS, MW 10k
PSB-80428-Arm PEG-SS, MW 20k
PSB-80448-Arm PEG-SS, MW 40k

8-Arm PEG-GAS (Multi-arm - eight arm - PEG Succinimidyl NHS ester)

8臂星形-聚乙二醇-戊酰胺琥珀酰亚胺酯

PSB-80518-Arm PEG-GAS, MW 10k
PSB-80528-Arm PEG-GAS, MW 20k
PSB-80548-Arm PEG-GAS, MW 40k

8-Arm PEG-SAS (Multi-arm - eight arm - PEG Succinimidyl NHS ester)

8臂星形-聚乙二醇-琥珀酰胺琥珀酰亚胺酯

PSB-80618-Arm PEG-SAS, MW 10k
PSB-80628-Arm PEG-SAS, MW 20k
PSB-80648-Arm PEG-SAS, MW 40k

8-Arm PEG-Hydrazide (Multi-arm - eight arm - PEG Hydrazide)

8臂星形-聚乙二醇-酰肼

PSB-81118-Arm PEG-Hydrazide, MW 10k
PSB-81128-Arm PEG-Hydrazide, MW 20k
PSB-81138-Arm PEG-Hydrazide, MW 40k

8-Arm PEG-SH (Multi-arm - eight arm - PEG SH sulfhydryl mecapto)

8臂星形-聚乙二醇-硫醇

PSB-8518-Arm PEG-SH, MW 10k
PSB-8528-Arm PEG-SH, MW 20k
PSB-8548-Arm PEG-SH, MW 40k

8-Arm PEG-MAL (Multi-arm - eight arm - PEG Maleimide)

8臂星形-聚乙二醇-马来酰亚胺

PSB-8618-Arm PEG-MAL, MW 10k
PSB-8628-Arm PEG-MAL, MW 20k
PSB-8648-Arm PEG-MAL, MW 40k

8-Arm PEG-OPSS (Multi-arm - eight arm - PEG Orthopyridyl Disulfide)

8臂星形-聚乙二醇-吡啶基二硫醚

PSB-8668-Arm PEG-OPSS, MW 10k
PSB-8678-Arm PEG-OPSS, MW 20k
PSB-8688-Arm PEG-OPSS, MW 40k

8-Arm PEG-VS (Eight armed PEG Vinylsulfone)

8臂星形-聚乙二醇-乙烯基砜

PSB-82218-Arm PEG-VS, MW 10k
PSB-82228-Arm PEG-VS, MW 20k
PSB-82238-Arm PEG-VS, MW 40k

8-Arm PEG-Epoxide (Multi-arm - eight arm - PEG Epoxide)

8臂星形-聚乙二醇-环氧基

PSB-8718-Arm PEG-Epoxide, MW 10k
PSB-8728-Arm PEG-Epoxide, MW 20k
PSB-8748-Arm PEG-Epoxide, MW 40k

8-Arm PEG-NPC (Multi-arm - eight arm - PEG Nitrophenyl Carbonate)

8臂星形-聚乙二醇-硝基苯碳酸酯

PSB-8778-Arm PEG-NPC, MW 10k
PSB-8788-Arm PEG-NPC, MW 20k
PSB-8798-Arm PEG-NPC, MW 40k

8-Arm PEG-Azide (Multi-arm PEG for azide alkyne click reaction)

8臂星形-聚乙二醇-叠氮基

PSB-8818-Arm PEG-Azide, MW 10k
PSB-8828-Arm PEG-Azide, MW 20k
PSB-8848-Arm PEG-Azide, MW 40k

8-Arm PEG-Alkyne (Eight arm PEG for azide alkyne click chemistry)

8臂星形-聚乙二醇-炔基

PSB-8868-Arm PEG-Alkyne, MW 10k
PSB-8878-Arm PEG-Alkyne, MW 20k
PSB-8898-Arm PEG-Alkyne, MW 40k

8-Arm PEG-Biotin (Multi-arm - eight arm - PEG Biotin)

8臂星形-聚乙二醇-生物素

PSB-8918-Arm PEG-Biotin, MW 10k
PSB-8928-Arm PEG-Biotin, MW 20k
PSB-8938-Arm PEG-Biotin, MW 40k

8-Arm PEG-Chloride (Multi-arm - eight arm - PEG Chloride)

8臂星形-聚乙二醇-氯

PSB-8948-Arm PEG-Chloride, MW 10k
PSB-8958-Arm PEG-Chloride, MW 20k
PSB-8968-Arm PEG-Chloride, MW 40k

8-Arm PEG-Tosylate (Multi-arm - eight arm - Tosyl PEG)

8臂星形-聚乙二醇-甲苯磺酸酯

PSB-8978-Arm PEG-Tosylate, MW 10k
PSB-8988-Arm PEG-Tosylate, MW 20k
PSB-8998-Arm PEG-Tosylate, MW 40k

8-Arm PEG-Norbornene

8臂星形-聚乙二醇-降冰片烯

PSB-81108-Arm PEG-Norbornene, MW 10k
PSB-82108-Arm PEG-Norbornene, MW 20k
PSB-83108-Arm PEG-Norbornene, MW 40k
8-Arm PEG-DBCO (DBCO Azide Click PEG Chemistry)
8臂星形-聚乙二醇-二苯并环辛烯(DBCO点击化学试剂)
PSB-80708-Arm PEG-DBCO, MW 10k
PSB-80718-Arm PEG-DBCO, MW 20k
PSB-80728-Arm PEG-DBCO, MW 40k

8-Arm PEG-X/Y (Bifunctional 8-Arm PEG with two functional groups)

8臂星形-聚乙二醇-X/Y(异双功能基)

Custom Synthesis8-Arm PEG-X/Y, MW 10k, 20k and 40k



Q: What are the differences among your PEG NHS ester & PEG Acid products?
A: We offer a variety of PEG Acid and PEG NHS ester. These NHS esters react with primary and secondary amine to form a stable amide linkage. This reaction may be carried out in an organic solution with an organic base or may be carried out in an aqueous solution at or around neutral pH or slightly acidic or basic. To PEGylate proteins or nanoparticles, it often requires a large excess of PEG NHS esters due to the competitive hydrolysis reaction in an aqueous solution. Stability of NHS esters is compared by their hydrolysis half-life (T1/2). To mitigate the competitive hydrolysis reaction, organic solvents such as amine-free, anhydrous DMF and DMSO may be used in combination with an aqueous buffer solution.

PEG NHS

esters

Structural characteristics

Amine

reactivity

Stability
Type A: SCMMethylene (CH2) linkage between PEG and NHS esterHighly reactiveHydrolysis half-life: less than five minutes. It often requires the use of a large excess of PEG reagents.
Type B: SGC4 aliphatic ester linkage between PEG and NHS esterVery reactiveHydrolysis half-life: around 20 minutes.
Type C: SSC3 aliphatic ester linkage between PEG and NHS esterVery reactiveHydrolysis half-life: around 10 minutes.
Type D: GASC4 aliphatic amide linkage between PEG and NHS esterVery reactiveHydrolysis half-life: around 20 minutes.
Type E: SASC3 aliphatic amide linkage between PEG and NHS esterVery reactiveHydrolysis half-life: around 10 minutes.

SCM: Succinimidyl Carboxyl Methyl ester; SG: Succinimidyl Glutarate ester; SS: Succinimidyl Succinate ester; GAS: GlutarAmide Succinimidyl ester; SAS: SuccinAmide Succinimidyl ester. Note: hydrolysis half-life depends on pH, temperature and other factors of the testing conditions.

PEG acidsStructural characteristics
Type A: AAMethylene (CH2) linkage between PEG and acid (COOH)
Type B: GAC4 aliphatic ester linkage between PEG and acid (COOH)
Type C: SAC3 aliphatic ester linkage between PEG and acid (COOH)
Type D: GAAC4 aliphatic amide linkage between PEG and acid (COOH)
Type E: SAAC3 aliphatic amide linkage between PEG and acid (COOH)
AA: Acetic Acid, also called CM - Carboxyl Methyl; GA: Glutaric Acid; SA: Succinic Acid; GAA: GlutarAmide Acid; SAS: SuccinAmide Acid.




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