Acrylate-PCL-PEG-PCL-Acyrlate 丙烯酸酯-聚己内酯-聚乙二醇-聚己内酯-丙烯酸酯 ABA三嵌段共聚物 生物降解高分子

Description:

The molecular weight of each block is shown in the parenthesis following the name of the block. PCL-PEG-PCL functionalized with acrylate can be used to prepare biodegradable PEG hydrogels through photopolymerization. Hydrolysis of esters of poly(caprolactone) block degrades the hydrophobic block and the entire crosslinked hydrogel network. Other functionalized PCL-PEG-PCL derivatives with bioreactive groups at the two terminals of the copolymer may be offered through custom synthesis.

References:

1) Biodegradable long-circulating polymeric nanospheres. Science 1994;363, Text.

2) Bioerodible Hydrogels Based on Photopolyrneried Poly(ethylene glycol)-co-poly(α-hydroxy acid) Diacrylate Macrorners, Macromolecules, 26, 1993: 581, Text.