| Acrylate-PLA-PEG-PLA-Acrylate (PLA-PEG-PLA functionalized with acrylate) |
|
| TL-10k-AC | Acrylate-PLA-PEG-PLA-Acrylate, PLA(1k)-PEG(10k)-PLA(1k) |
| TL-1k-AC | Acrylate-PLA-PEG-PLA-Acrylate, PLA(1k)-PEG(1k)-PLA(1k) |
| TL-20k-AC | Acrylate-PLA-PEG-PLA-Acrylate, PLA(1k)-PEG(20k)-PLA(1k) |
| TL-2k-AC | Acrylate-PLA-PEG-PLA-Acrylate, PLA(1k)-PEG(2k)-PLA(1k) |
| TL-5k-AC | Acrylate-PLA-PEG-PLA-Acrylate, PLA(1k)-PEG(5k)-PLA(1k) |
Description:
The molecular weight of each block is shown in the parenthesis following the name of the block. PLA-PEG-PLA functionalized with acrylate can be used to prepare biodegradable PEG hydrogels through photopolymerization. Hydrolysis of esters of poly(lactic acid) block degrades the hydrophobic block and the entire crosslinked hydrogel network. Other functionalized PLA-PEG-PLA derivatives with bioreactive groups at the two terminals of the copolymer may be offered through custom synthesis.
References:
1) Biodegradable long-circulating polymeric nanospheres. Science 1994;363:1600–3, Text.
2) Bioerodible Hydrogels Based on Photopolyrneried Poly(ethylene glycol)-co-poly(α-hydroxy acid) Diacrylate Macrorners, Macromolecules, 26, 1993: 581—537, Text.
沪公网安备31011702007691号 | 沪ICP备2023018337号-1
推荐链接：